The SciLog® NFF is a proven platform for use in discovery to production-scale applications including viral filtration, cell harvesting, chromatography column loading, as well as clarification and sterilization. The system automatically monitors, adjusts and documents pressures and flow rate to optimize processing times and maximize filter life and efficiency. Using the onboard sensors and automation we eliminate the need for constant monitoring during production runs.
Via a color touch screen and pre-installed operational software, users have the ability to execute a normal flow filtration process via four different control methods: Constant rate NFF, Constant Pressure NFF, R/P Stat Method and Manual Operation
The system can optimize your filtration throughput by up to 30 percent while communicating real time process parameters via OPC to a plant historian. Up to two optional integrated scales can be used to deliver filtration precision by gravimetrically controlling operations.
R/P Stat Method
The SciLog® NFF System incorporates the patented R/P Stat Method, an innovation which has resulted in significant improvements in filter life expectancy. This is done by selecting three simple process variables including initial flow rate, maximum inlet pressure, and minimum flow rate.
By using the R/P Stat Method, as the membrane begins to foul, the NFF system dynamically adjusts the flow rate which allows additional product to pass through the filter before the membrane fouls. As a result, the R/P Stat method can provide up to 30% increase in filtration yield.
Features and Benefits
• Walk-away automation improves filter throughput using patented rate pressure controlled feed
• Options for fully disposable, semi-disposable or stainless CIP flowpaths
• Configurable tof multiple or flexible processes
• Accommodates any commercially available filter
• Touch-screen interface with optional OPC connectivity for process documentation or remote control
• Mobile and compact base
• User configurable alarms and interlocks
• Optional integrated scale for highly accurate filtration endpoints
